Circulating MicroRNA Is a Biomarker of Pediatric Crohn Disease
نویسندگان
چکیده
منابع مشابه
Role of microRNA as a biomarker in Alzheimer’s disease
Introduction: MicroRNAs are small, non-coding, and protected RNA molecules that regulate gene expression after transcription by mRNA degradation or inhibition of protein synthesis. The function of these molecules is critical to many cellular processes, including growth, development, differentiation, homeostasis, apoptosis, aging, stress resistance. In addition, some diseases including cancer, a...
متن کاملEvaluation of Extracellular Circulating Human MicroRNA-197 as a Target Biomarker in Patients with Coronary Artery Disease
Background: Coronary Artery Disease (CAD) refers to the reduction or blockage of all or part of the coronary arteries due to the process of atherosclerosis or the presence of a clot. The aim of this study was to investigate the association of serum miR-197 as a diagnostic index in patients with coronary artery disease. Methods: In this study, 100 patients with CAD were selected. Extraction of...
متن کاملCirculating microRNA-137 is a potential biomarker for human glioblastoma.
OBJECTIVE In this study, we investigated whether circulating microRNA-137 (miR-137) could be a potential biomarker for patients with glioblastoma (GBM). PATIENTS AND METHODS Serum samples were collected from 64 GBM patients and 64 healthy controls. The expression level of circulating miR-137 was compared by quantitative RT-PCR. Among GBM patients, circulating miR-137 was compared between pati...
متن کاملCirculating microRNA-196a is an early gastric cancer biomarker
MicroRNA-196a (miRNA-196a) is associated with the development of gastric cancer and metastasis. Intestinal metaplasia and low- or high-grade dysplasia are considered to be precursors of intestinal type gastric cancer. Accordingly, we investigated the expression of plasma miRNA-196a as an early detection biomarker in precancerous gastric lesions and early cancer (pT1a/b), which is otherwise trea...
متن کاملCirculating MicroRNA223 is a New Biomarker for Inflammatory Bowel Disease
Endoscopy is an important tool in screening and monitoring inflammatory bowel disease (IBD); however, it is invasive, costly, and associated with risks to the patients. Recently, circulating microRNAs (miRNAs) have emerged as promising noninvasive biomarkers. We proposed that the expression of serum microRNA223 (miR-223) could be a biomarker for IBD.Studies were conducted using serum samples fr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pediatric Gastroenterology & Nutrition
سال: 2011
ISSN: 0277-2116
DOI: 10.1097/mpg.0b013e31822200cc